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Article

Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor

28 Apr 2020

Abstract excerpt

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive soft-tissue malignancy with a poor overall survival and no effective therapeutic options. The tumor is believed to be dependent on the continued activity of the oncogenic EWS-WT1 transcription factor. However, the dependence of the tumor on EWS-WT1 has not been well established. In addition, there are no studies exploring the downstream...

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PMID: 32345977
DOI: 10.1038/s41389-020-0224-1

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