Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeutics

30 Jul 2024

Abstract excerpt

Desmoplastic Small Round Cell Tumor (DSRCT) is a highly aggressive pediatric cancer caused by a reciprocal translocation between chromosomes 11 and 22, leading to the formation of the EWSR1::WT1 oncoprotein. DSRCT presents most commonly in the abdominal and pelvic peritoneum and remains refractory to current treatment regimens which include chemotherapy, radiotherapy, and surgery. As a rare cancer, sample and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Protein Degradation and Inhibitors
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39139449
DOI: 10.3389/fcell.2024.1442488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeuticsPMID 39139449Read ↗

Establishment of multiple novel patient-derived models of desmoplastic small round cell tumor enabling functional characterization of ERBB pathway signaling and pre-clinical evaluation of a novel targeted therapy approachSemantic proximity Read ↗

Desmoplastic Small Round Cell Tumor: A Review of Main Molecular Abnormalities and Emerging TherapySemantic proximity Read ↗

Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell TumorsSemantic proximity Read ↗

Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children’s Oncology GroupSemantic proximity Read ↗

Comprehensive Molecular Profiling of Desmoplastic Small Round Cell TumorSemantic proximity Read ↗

A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive diseaseSemantic proximity Read ↗

Desmoplastic Small Round Cell TumorSemantic proximity Read ↗

EWSR1-WT1 Target Genes and Therapeutic Options Identified in a Novel DSRCT In Vitro ModelSemantic proximity Read ↗

Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell TumorSemantic proximity Read ↗

Genomic and Proteomic Alterations in Desmoplastic Small Round Blue-Cell TumorsSemantic proximity Read ↗

Desmoplastic Small Round Cell Tumor 20 Years After its DiscoverySemantic proximity Read ↗

Super-enhancer-driven <i>CACNA2D2</i> is an EWSR1::WT1 signature gene encoding a diagnostic marker for desmoplastic small round cell tumor (DSRCT)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.