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Genomic and Proteomic Alterations in Desmoplastic Small Round Blue-Cell Tumors

1 Jun 2018

Abstract excerpt

Purpose Desmoplastic small round blue-cell tumors (DSRCTs) are sarcomas that contain the t(11;22) (p13;q12) translocation EWS-WT1 fusion protein. Because this is a rare tumor type, prospective clinical trials in DSRCT are challenging. Patients are treated in a manner similar to those with Ewing sarcoma; however, differences in prognosis and clinical presentation suggest fundamental differences in biology and...

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PMID: 32913982
DOI: 10.1200/po.17.00170

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