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Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor

22 Mar 2021

Abstract excerpt

Abstract Desmoplastic small round cell tumor (DSRCT) is characterized by the EWSR1–WT1 t(11;22) (p13:q12) translocation. Few additional putative drivers have been identified, and research has suffered from a lack of model systems. Next-generation sequencing (NGS) data from 68 matched tumor-normal samples, whole-genome sequencing data from 10 samples, transcriptomic and affymetrix array data, and a bank of DSRCT...

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PMID: 33753552
DOI: 10.1158/1541-7786.mcr-20-0722

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