Article
Animal products and K-ras codon 12 and 13 mutations in colon carcinomas.
Carcinogenesis - 1 Feb 2000
Kampman E, Voskuil D W, van Kraats A A, Balder H F, van Muijen G N, Goldbohm R A, van't Veer P
Abstract excerpt
K-ras gene mutations (codons 12 and 13) were determined by PCR-based mutant allele-specific amplification (MASA) in tumour tissue of 185 colon cancer patients: 36% harboured mutations, of which 82% were located in codon 12. High intakes of animal protein, calcium and poultry were differently associated with codon 12 and 13 mutations: odds ratios (OR) and 95% confidence intervals (95% CI) for codon 12 versus codon...
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