Article
Animal products and K-ras codon 12 and 13 mutations in colon carcinomas.
Carcinogenesis - 1 Feb 2000
Kampman E, Voskuil D W, van Kraats A A, Balder H F, van Muijen G N, Goldbohm R A, van't Veer P
Abstract excerpt
K-ras gene mutations (codons 12 and 13) were determined by PCR-based mutant allele-specific amplification (MASA) in tumour tissue of 185 colon cancer patients: 36% harboured mutations, of which 82% were located in codon 12. High intakes of animal protein, calcium and poultry were differently asso...
Topics
- Adult
- Aged
- Animals
- Calcium, Dietary
- Carcinoma
- Case-Control Studies
- Codon
- Colonic Neoplasms
- DNA Adducts
- DNA Mutational Analysis
- DNA, Neoplasm
- Dairy Products
- Dietary Fats