Article
Detection and analysis of four polymorphic markers at the human monoamine oxidase (MAO) gene in Japanese controls and patients with Parkinson's disease.
Biochemical and biophysical research communications - 18 Jun 1998
Nakatome M, Tun Z, Shimada S, Honda K
Abstract excerpt
Monoamine oxidase (MAO), which exists in two forms (MAOA and MAOB), plays an important role in the oxidative metabolism of neurotransmitters such as dopamine, and has been implicated in the etiology of Parkinson's disease (PD). Individual variations in the activity of these enzymes appear to be g...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Case-Control Studies
- DNA Primers
- Female
- Gene Frequency
- Genetic Markers
- Genetic Variation
- Haplotypes