Article
Structure and selection of hepatitis B virus variants during the natural course of infection and interferon therapy.
Princess Takamatsu symposia - 1 Jan 1995
Günther S, Miska S, Meisel H, Will H
Abstract excerpt
The consequences of hepatitis B virus (HBV) infection range from asymptomatic transient and chronic infections to mild and severe forms of hepatitis up to the development of liver cirrhosis and hepatocellular carcinoma. Immune-mediated destruction of infected liver cells plays a major role in HBV pathogenesis. Escape from immune-recognition by changing the antigenic make-up of HBV or by preventing the expression...
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