Article
Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells.
British journal of cancer - 26 Jan 2004
Hofer M D, Menke A, Genze F, Gierschik P, Giehl K
Abstract excerpt
The human metastasis-associated protein 1 (MTA1) is a constituent of the nucleosome-remodelling and -deacetylation complex. Its expression has been correlated with the invasion and metastasis of epithelial neoplasms. To address the functional consequences of MTA1 expression in pancreatic carcinoma cells, we have established PANC-1 pancreatic carcinoma cells that stably express MTA1 as an enhanced green...
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