Article
Generation of alloantigen-stimulated anti-human immunodeficiency virus activity is associated with HLA-A*02 expression.
The Journal of infectious diseases - 1 Feb 2001
Grene E, Pinto L A, Cohen S S, Mac Trubey C, Trivett M T, Simonis T B, Liewehr D J, Steinberg S M, Shearer G M
Abstract excerpt
Stimulation of peripheral blood mononuclear cells (PBMC) with allogeneic PBMC (ALLO) can result in activity that inhibits the replication of human immunodeficiency virus (HIV). The present study demonstrates that strong anti-HIV activity is dependent on expression of HLA-A*02 by the responding PBMC. Anti-HIV activity was equally effective against 2 primary isolates that use different coreceptors. Neither...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.