Article
A genetic approach for analysing surface-exposed regions of the OmpC protein of Escherichia coli K-12.
Molecular microbiology - 1 Feb 1996
Vakharia H, Misra R
Abstract excerpt
Phage attachment sites on bacterial cell surfaces are provided by the exposed regions of outer membrane proteins and lipopolysaccharide (LPS). We have identified surface exposed residues of OmpC that are important for phage binding. This was accomplished by employing a genetic scheme in which two simultaneous selections enriched for ompC mutants defective in phage attachment, but retained functional channels....
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