Article
A naturally occurring novel allele of Escherichia coli outer membrane protein A reduces sensitivity to bacteriophage.
Applied and environmental microbiology - 1 Dec 2006
Power Michelle L, Ferrari Belinda C, Littlefield-Wyer Jane, Gordon David M, Slade Martin B, Veal Duncan A
Abstract excerpt
A novel Escherichia coli outer membrane protein A (OmpA) was discovered through a proteomic investigation of cell surface proteins. DNA polymorphisms were localized to regions encoding the protein's surface-exposed loops which are known phage receptor sites. Bacteriophage sensitivity testing indicated an association between bacteriophage resistance and isolates having the novel ompA allele.
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