Article
Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity.
The Plant journal : for cell and molecular biology - 1 Feb 1996
Park Y D, Papp I, Moscone E A, Iglesias V A, Vaucheret H, Matzke A J, Matzke M A
Abstract excerpt
The promoter homology-dependent inactivation of a 35Spro-hygromycin phosphotransferase (hpt) gene, which is present at the H2 locus, by the multipurpose 271 silencing locus has been studied. The 271 locus can silence any gene under the control of the 35Spro as well as endogenous nitrite reductase (NiR) genes of tobacco because of the presence of a chimeric antisense gene (35Spro-RiN). All F1 progeny of a cross...
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