Article
TCR Vβ Evaluation by Flow Cytometry.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Peruzzi Benedetta, Bencini Sara, Caporale Roberto
Abstract excerpt
T-cell receptor (TCR)-Vβ repertoire analysis is a sensitive method for detection of T-cell clonality. This type of analysis has been used for studying selective T-cell responses in autoimmune disease, alloreactivity in transplantation, and protective immunity against microbial and tumor antigens and in neoplastic T cells. Here, we describe the flow cytometric methods to perform this analysis.
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