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Article

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania.

Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 1996

Mukhopadhyay R, Dey S, Xu N, Gage D, Lightbody J, Ouellette M, Rosen B P

Abstract excerpt

Leishmania resistant to arsenicals and antimonials extrude arsenite. Previous results of arsenite uptake into plasma membrane-enriched vesicles suggested that the transported species is a thiol adduct of arsenite. In this paper, we demonstrate that promastigotes of arsenite-resistant Leishmania t...

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Identifiers

PMID: 8816809
DOI: 10.1073/pnas.93.19.10383
PMCID: PMC38393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8816809-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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