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Article

Opposite effects of Ni2+ on Xenopus and rat ENaCs expressed in Xenopus oocytes.

American journal of physiology. Cell physiology - 1 Oct 2005

Cucu Dana, Simaels Jeannine, Eggermont Jan, Van Driessche Willy, Zeiske Wolfgang

Abstract excerpt

The epithelial Na+ channel (ENaC) is modulated by various extracellular factors, including Na+, organic or inorganic cations, and serine proteases. To identify the effect of the divalent Ni2+ cation on ENaCs, we compared the Na+ permeability and amiloride kinetics of Xenopus ENaCs (xENaCs) and rat ENaCs (rENaCs) heterologously expressed in Xenopus oocytes. We found that the channel cloned from the kidney of the...

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Identifiers

PMID: 15944207
DOI: 10.1152/ajpcell.00419.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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