Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Opposite effects of Ni2+ on Xenopus and rat ENaCs expressed in Xenopus oocytes.

American journal of physiology. Cell physiology - 1 Oct 2005

Cucu Dana, Simaels Jeannine, Eggermont Jan, Van Driessche Willy, Zeiske Wolfgang

Abstract excerpt

The epithelial Na+ channel (ENaC) is modulated by various extracellular factors, including Na+, organic or inorganic cations, and serine proteases. To identify the effect of the divalent Ni2+ cation on ENaCs, we compared the Na+ permeability and amiloride kinetics of Xenopus ENaCs (xENaCs) and ra...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amiloride
Share to Diuretics
Share to Electrophysiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Sodium Channels

Share to Membrane Potentials

Share to Nickel

Share to Sodium Channels

Share to Xenopus

Source

Identifiers

PMID: 15944207
DOI: 10.1152/ajpcell.00419.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15944207-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Opposite effects of Ni2+ on Xenopus and rat ENaCs expressed in Xenopus oocytes.PMID 15944207Read ↗

External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.Semantic proximity Read ↗

Side chain orientation of residues lining the selectivity filter of epithelial Na+ channels.Semantic proximity Read ↗

Open probability of the epithelial sodium channel is regulated by intracellular sodium.Semantic proximity Read ↗

The epithelial sodium channel (ENaC): new insights into ENaC gating.Semantic proximity Read ↗

On the molecular basis of ion permeation in the epithelial Na+ channel.Semantic proximity Read ↗

Extracellular histidine residues crucial for Na+ self-inhibition of epithelial Na+ channels.Semantic proximity Read ↗

Different cation sensitivities and binding site domains of Na+-Ca2+-K+ and Na+-Ca2+ exchangers.Semantic proximity Read ↗

Novel determinants of epithelial sodium channel gating within extracellular thumb domains.Semantic proximity Read ↗

Regulation and amiloride-binding site of epithelial Na+ channels.Semantic proximity Read ↗

Voltage-dependent inhibition of the sodium pump by external sodium: species differences and possible role of the N-terminus of the alpha-subunit.Semantic proximity Read ↗

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels.Semantic proximity Read ↗

Residues important for Ca2+ ion transport in the neuronal K+-dependent Na+-Ca2+ exchanger (NCKX2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.