C-KI-RAS activation and the biological behaviour of proximal and distal colonic adenocarcinomas.

doi:10.1016/0959-8049(95)00567-6

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Article

C-KI-RAS activation and the biological behaviour of proximal and distal colonic adenocarcinomas.

European journal of cancer (Oxford, England : 1990) - 1 Mar 1996

Elnatan J, Goh H S, Smith D R

Abstract excerpt

One hundred and forty colonic adenocarcinomas originating on the left side of the colorectum and 70 colorectal carcinomas originating on right side of the colorectum were examined for activating mutations of codons 12 and 13 of the C-KI-RAS proto-oncogene. Rates of mutation were significantly different (right colon 43%, 30/70 versus left colon 23%, 32/140; P = 0.0025). Adenocarcinomas from the left side of the...

Topics

Adenocarcinoma
Age Factors
Base Sequence
Colorectal Neoplasms
Female
Gene Expression Regulation
Genes, ras
Humans
Male
Molecular Sequence Data
Mutation
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Polymerase Chain Reaction

Prognosis

Proto-Oncogene Mas

Sex Factors

Survival Rate

Source

Open in PubMed

Identifiers

PMID: 8814697
DOI: 10.1016/0959-8049(95)00567-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8814697-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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