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Article

Inhibition of cell wall turnover and autolysis by vancomycin in a highly vancomycin-resistant mutant of Staphylococcus aureus.

Journal of bacteriology - 1 Apr 1997

Sieradzki K, Tomasz A

Abstract excerpt

A highly vancomycin-resistant mutant (MIC = 100 microg/ml) of Staphylococcus aureus, mutant VM, which was isolated in the laboratory by a step-pressure procedure, continued to grow and synthesize peptidoglycan in the presence of vancomycin (50 microg/ml) in the medium, but the antibiotic completely inhibited cell wall turnover and autolysis, resulting in the accumulation of cell wall material at the cell surface...

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Identifiers

PMID: 9098053
DOI: 10.1128/jb.179.8.2557-2566.1997
PMCID: PMC179004

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Source receipt: pubmed, retrieved 7 Sept 2026.

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