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Article

Function of Xenopus Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Cl- Channels and Use of Human-Xenopus Chimeras to Investigate the Pore Properties of CFTR

1 Oct 1996

Abstract excerpt

To explore the relationship between structure and function in the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel, we studied Xenopus CFTR. We found that the anion permeability sequence of cAMP-activated Cl- currents in the apical membrane of Xenopus A6 epithelia differed from that of cAMP-activated Cl- currents in human epithelia expressing CFTR. To understand the molecular basis for this...

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Share to Advanced biosensing and bioanalysis techniques
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Identifiers

PMID: 8810276
DOI: 10.1074/jbc.271.41.25184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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