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Article

Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis.

American journal of respiratory cell and molecular biology - 1 Jan 2011

Antigny Fabrice, Norez Caroline, Dannhoffer Luc, Bertrand Johanna, Raveau Dorothée, Corbi Pierre, Jayle Christophe, Becq Frédéric, Vandebrouck Clarisse

Abstract excerpt

In cystic fibrosis (CF), abnormal control of cellular Ca(2+) homeostasis is observed. We hypothesized that transient receptor potential canonical (TRPC) channels could be a link between the abnormal Ca(2+) concentrations in CF cells and cystic fibrosis transmembrane conductance regulator (CFTR) d...

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Source

Identifiers

PMID: 20203293
DOI: 10.1165/rcmb.2009-0347OC

Genes

CFTR
TRPC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20203293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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