Article
Mutations that alter the transmembrane signalling pathway in an ATP binding cassette (ABC) transporter.
The EMBO journal - 1 Apr 1994
Covitz K M, Panagiotidis C H, Hor L I, Reyes M, Treptow N A, Shuman H A
Abstract excerpt
The maltose transport system of Escherichia coli is a well-characterized member of the ATP binding cassette transporter superfamily. Members of this family share sequence similarity surrounding two short sequences (the Walker A and B sequences) which constitute a nucleotide binding pocket. It is likely that the energy from binding and hydrolysis of ATP is used to accomplish the translocation of substrate from one...
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