Article
Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors.
Journal of lipid research - 1 Jun 1996
Bohnet K, Pillot T, Visvikis S, Sabolovic N, Siest G
Abstract excerpt
The clinical relevance of apoE concentration in lipoprotein fractions should be evaluated. We investigated the impact of the common apolipoprotein (apo) E polymorphism in conjunction with very low density lipoprotein (VLDL) apoE concentration on the receptor binding properties of VLDL preparations from 17 normolipidemic subjects of the HepG2 cell surface receptors. All six apoE genotypes were studied. When apoE...
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