Article
From cholesterol transport to signal transduction: low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2.
Biochimica et biophysica acta - 15 Dec 2000
Nimpf J, Schneider W J
Abstract excerpt
The discovery of an ever growing number of low density lipoprotein (LDL) receptor gene family members has triggered research into many different directions. Here we first summarize the results of classical studies on the role of the LDL receptor in cholesterol transport, the structure/function relationships delineated with the help of LDL receptor mutations in familial hypercholesterolemia, and the elegant way in...
Topics
- Animals
- Apolipoprotein E2
- Apolipoproteins E
- Biological Transport
- Cell Adhesion Molecules, Neuronal
- Cholesterol
- Extracellular Matrix Proteins
- Humans
- Lipoproteins, VLDL
- Low Density Lipoprotein Receptor-Related Protein-1
- Mutation
- Nerve Tissue Proteins
- RNA Splicing