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Article

Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage.

Genetics - 1 Jul 1996

Sweder K S, Verhage R A, Crowley D J, Crouse G F, Brouwer J, Hanawalt P C

Abstract excerpt

Transcription-coupled repair, the targeted repair of the transcribed strands of active genes, is defective in bacteria, yeast, and human cells carrying mutations in mfd, RAD26 and ERCC6, respectively. Other factors probably are also uniquely involved in transcription-repair coupling. Recently, a defect was described in transcription-coupled repair for Escherichia coli mismatch repair mutants and human tumor cell...

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Source

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Identifiers

PMID: 8807287
DOI: 10.1093/genetics/143.3.1127
PMCID: PMC1207384

Genes

MSH2
ERCC6
MLH1
MSH3
PMS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage.PMID 8807287Read ↗

Transcription-coupled repair deficiency and mutations in human mismatch repair genes.Semantic proximity Read ↗

Analysis of yeast MSH2-MSH6 suggests that the initiation of mismatch repair can be separated into discrete steps.Semantic proximity Read ↗

A mutation in the MSH5 gene results in alkylation tolerance.Semantic proximity Read ↗

Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System.Semantic proximity Read ↗

Differential involvement of the human mismatch repair proteins, hMLH1 and hMSH2, in transcription-coupled repair.Semantic proximity Read ↗

Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level.Semantic proximity Read ↗

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3Semantic proximity Read ↗

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.Semantic proximity Read ↗

A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition.Semantic proximity Read ↗

The yeast RAD2, but not RAD1, gene is involved in the transcription-coupled repair of thymine glycols.Semantic proximity Read ↗

Saccharomyces cerevisiae mms19 mutants are deficient in transcription-coupled and global nucleotide excision repair.Semantic proximity Read ↗

Physical interaction between components of DNA mismatch repair and nucleotide excision repair.Semantic proximity Read ↗

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