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Article

Failure to unwind causes cancer. Genome stability.

Current biology : CB - 1 Mar 1996

Watt P M, Hickson I D

Abstract excerpt

The recent cloning of the gene defective in individuals with Bloom's syndrome has revealed a link between DNA helicases, genetic instability and a predisposition to cancer.

Read the complete abstract on PubMed

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Share to Adenosine Triphosphatases
Share to Bloom Syndrome
Share to DNA Helicases
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8805238
DOI: 10.1016/s0960-9822(02)00474-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Failure to unwind causes cancer. Genome stability.PMID 8805238Read ↗

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Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.Semantic proximity Read ↗

Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.Semantic proximity Read ↗

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