Article
Age-dependent expression of osteoblastic phenotypic markers in normal human osteoblasts cultured long-term in the presence of dexamethasone.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jan 1995
Sutherland M S, Rao L G, Muzaffar S A, Wylie J N, Wong M M, McBroom R J, Murray T M
Abstract excerpt
We have previously shown that osteoblasts derived from trabecular bone explants and cultured long term in 10 nM dexamethasone ((HOB + DEX) cells) exhibited properties consistent with a more differentiated phenotype compared with those grown in the absence of dexamethasone ((HOB-DEX) cells). To ch...
Topics
- Adenylyl Cyclases
- Adolescent
- Adult
- Age Factors
- Aged
- Alkaline Phosphatase
- Cell Division
- Cells, Cultured
- Dexamethasone
- Female
- Humans
- Male
- Middle Aged
- Osteoblasts
- Phenotype