Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.

doi:10.1128/JVI.70.10.6862-6869.1996

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Article

Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.

Journal of virology - 1 Oct 1996

Demers G W, Espling E, Harry J B, Etscheid B G, Galloway D A

Abstract excerpt

Cells arrest in the G1 or G0 phase of the cell cycle in response to a variety of negative growth signals that induce arrest by different molecular pathways. The ability of human papillomavirus (HPV) oncogenes to bypass these signals and allow cells to progress into the S phase probably contribute...

Topics

Cell Cycle
Cell Transformation, Viral
Epithelium
Humans
Mutation
Oncogene Proteins, Viral
Organ Culture Techniques
Papillomaviridae
Papillomavirus E7 Proteins
Sequence Analysis

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