Article
YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity.
Journal of virology - 1 Oct 1996
O'Connor M J, Tan S H, Tan C H, Bernard H U
Abstract excerpt
YY1 is a multifunctional transcription factor that has been shown to regulate the expression of a number of cellular and viral genes, including the human papillomavirus (HPV) oncogenes E6 and E7. In this study, we have analyzed the YY1-mediated repression of the HPV type 16 (HPV-16) E6-E7 promote...
Topics
- DNA-Binding Proteins
- Erythroid-Specific DNA-Binding Factors
- Gene Expression Regulation, Viral
- HeLa Cells
- Humans
- Mutation
- Papillomaviridae
- Transcription Factor AP-1
- Transcription Factors
- Transcription, Genetic
- YY1 Transcription Factor
