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Article

YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity.

Journal of virology - 1 Oct 1996

O'Connor M J, Tan S H, Tan C H, Bernard H U

Abstract excerpt

YY1 is a multifunctional transcription factor that has been shown to regulate the expression of a number of cellular and viral genes, including the human papillomavirus (HPV) oncogenes E6 and E7. In this study, we have analyzed the YY1-mediated repression of the HPV type 16 (HPV-16) E6-E7 promoter. A systematic analysis to identify YY1 sites present in the HPV-16 long control region showed that of 30 potential...

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Identifiers

PMID: 8794287
DOI: 10.1128/JVI.70.10.6529-6539.1996
PMCID: PMC190693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity.PMID 8794287Read ↗

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Yin Yang 1 Negatively Regulates the Differentiation-Specific E1 Promoter of Human Papillomavirus Type 6Semantic proximity Read ↗

Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.Semantic proximity Read ↗

Dual Role of YY1 in HPV Life Cycle and Cervical Cancer DevelopmentSemantic proximity Read ↗

The E6/E7 promoter of extrachromosomal HPV16 DNA in cervical cancers escapes from cellular repression by mutation of target sequences for YY1.Semantic proximity Read ↗

The Nuclear Factor YY1 Suppresses the Human Gamma Interferon Promoter through Two Mechanisms: Inhibition of AP1 Binding and Activation of a Silencer ElementSemantic proximity Read ↗

A switch region determines the cell type-specific positive or negative action of YY1 on the activity of the human papillomavirus type 18 promoterSemantic proximity Read ↗

Binding of the human papillomavirus type 16 p97 promoter by the adeno-associated virus Rep78 major regulatory protein correlates with inhibition.Semantic proximity Read ↗

Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcriptionSemantic proximity Read ↗

An Upstream YY1 Binding Site on the HIV-1 LTR Contributes to Latent InfectionSemantic proximity Read ↗

Regulation of Yin Yang 1 by Tyrosine Phosphorylation.Semantic proximity Read ↗

YY1 as a regulator of replication-dependent hamster histone H3.2 promoter and an interactive partner of AP-2.Semantic proximity Read ↗

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