Article
YY1 as a regulator of replication-dependent hamster histone H3.2 promoter and an interactive partner of AP-2.
The Journal of biological chemistry - 5 Jan 2001
Wu F, Lee A S
Abstract excerpt
In analyzing cis-regulatory elements important for cell cycle control of the replication-dependent hamster histone H3.2 gene, we discovered a binding site for the transcription factor YY1 embedded within GC-rich sequences between the two tandem CCAAT repeats proximal to the TATA element. Base mutations that specifically eliminated YY1 binding resulted in suppression of the S phase induction of the H3.2 promoter....
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