Article
Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.
The EMBO journal - 1 Dec 1992
Bauknecht T, Angel P, Royer H D, zur Hausen H
Abstract excerpt
The human papillomavirus type 18 (HPV-18) promoter contains a TPA responsive element (TRE) which confers TPA responsiveness on a heterologous promoter. In the context of the HPV-18 promoter, however, this AP-1 site is inactive. We have identified a negative regulatory domain in the HPV-18 promoter which represses the constitutive and TPA-induced AP-1 activity. This negative regulatory sequence has been mapped to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
