Article
Blunted coronary reserve in myotonic dystrophy. An early and gene-related phenomenon.
Circulation - 1 Sept 1996
Annane D, Merlet P, Radvanyi H, Mazoyer B, Eymard B, Fiorelli M, Junien C, Fardeau M, Ounnoughene Z, Gajdos P, Syrota A, Duboc D
Abstract excerpt
BACKGROUND: In myotonic dystrophy (DM), striated muscle is involved in relation to the size of the DNA mutation. Smooth muscle may be similarly impaired at the level of the urinary and digestive apparatus and possibly at the level of small vessels, since microangiopathy has been described in the iris and digital capillaries. Our purpose was to study the function of the myocardial microvasculature in relation to...
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