Correlation between decreased myocardial glucose phosphorylation and the DNA mutation size in myotonic dystrophy.

doi:10.1161/01.cir.90.6.2629

Back to search

Article

Correlation between decreased myocardial glucose phosphorylation and the DNA mutation size in myotonic dystrophy.

Circulation - 1 Dec 1994

Annane D, Duboc D, Mazoyer B, Merlet P, Fiorelli M, Eymard B, Radvanyi H, Junien C, Fardeau M, Gajdos P

Abstract excerpt

BACKGROUND: Myotonic dystrophy, the most common form of adult dystrophy, has been shown to be caused by amplification of CTG triplet repeat in the 3' untranslated region of a protein kinase gene located on chromosome 19. Impaired glucose metabolism has been suggested as a possible explanation of...

Topics

Adult
DNA
Deoxyglucose
Female
Fluorodeoxyglucose F18
Glucose
Heart
Humans
Male
Middle Aged
Mutation
Myocardium
Myotonic Dystrophy
Phosphorylation
Tomography, Emission-Computed

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.