An oliogenic disease displaying weak marker associations: a summary of contributions to problem 1 of GAW9.

doi:10.1002/gepi.1370120604

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Article

An oliogenic disease displaying weak marker associations: a summary of contributions to problem 1 of GAW9.

Genetic epidemiology - 1 Jan 1995

Hodge S E

Abstract excerpt

Problem 1 consisted of artificial data simulated from an oligogenic (four-locus) disease model. The data set contained 200 nuclear families with at least one affected child and 100 control families with no affected members. Two of the disease loci were intended to be detectable via association an...

Topics

Chromosome Mapping
Female
Genetic Diseases, Inborn
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Humans
Male
Models, Genetic
Risk Factors

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