Article
An oliogenic disease displaying weak marker associations: a summary of contributions to problem 1 of GAW9.
Genetic epidemiology - 1 Jan 1995
Hodge S E
Abstract excerpt
Problem 1 consisted of artificial data simulated from an oligogenic (four-locus) disease model. The data set contained 200 nuclear families with at least one affected child and 100 control families with no affected members. Two of the disease loci were intended to be detectable via association analysis but not necessarily via linkage analysis, and the other two were virtually undetectable in this data set....
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