Article
Genetic analysis workshop 9: development of problem 1.
Genetic epidemiology - 1 Jan 1995
Hodge S E
Abstract excerpt
Problem 1 was designed to involve an oligogenic model with four "disease susceptibility" loci, such that all individuals with at least four "upper-case" alleles were at equal risk to be affected (and those with three or fewer were not at risk). Two of these loci were identical to marker loci, thus giving rise to weak disease-marker associations. The other two were located between marker loci, with no linkage...
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