Article
Apolipoprotein E genotype in Spanish schizophrenic patients.
Psychiatric genetics - 1 Jun 2000
Durany N, Riederer P, Cruz-Sánchez F F
Abstract excerpt
Apolipoprotein E (ApoE) is a lipoprotein that, in the central nervous system, is thought to play a role in neuronal growth and repair. ApoE has three isoforms (ApoE2, ApoE3 and ApoE4) coded by three different alleles (epsilon2, epsilon3 and epsilon4). Evidence from family, twin and adoption studies suggest that there is an important genetic contribution to the etiology of schizophrenia. Schizophrenia is in some...
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