Article
A Dictystelium mutant with defective aggregate size determination.
Development (Cambridge, England) - 1 Sept 1996
Brock D A, Buczynski G, Spann T P, Wood S A, Cardelli J, Gomer R H
Abstract excerpt
Starved Dictyostelium cells aggregate into groups of roughly 10(5) cells. We have identified a gene which, when repressed by antisense transformation or homologous recombination, causes starved cells to form large numbers of small aggregates. We call the gene smlA for small aggregates. A roughly...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Western
- Cell Adhesion Molecules
- Cell Cycle
- Culture Media, Conditioned
- Cyclic AMP
- DNA, Antisense
- Dextrans
- Dictyostelium
- Electrophoresis, Polyacrylamide Gel
- Exocytosis
- Fluorescein-5-isothiocyanate
- Fluorescent Antibody Technique
- Fungal Proteins
- Gene Expression Regulation, Fungal