Article
A cell-counting factor regulating structure size in Dictyostelium.
Genes & development - 1 Aug 1999
Brock D A, Gomer R H
Abstract excerpt
Developing Dictyostelium cells form large aggregation streams that break up into groups of 0.2 x 10(5) to 1 x 10(5) cells. Each group then becomes a fruiting body. smlA cells oversecrete an unknown factor that causes aggregation streams to break up into groups of approximately 5 x 10(3) cells and thus form very small fruiting bodies. We have purified the counting factor and find that it behaves as a complex of...
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