Article
Candidate gene approach of familial morbid obesity: linkage analysis of the glucocorticoid receptor gene.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Jun 1996
Clément K, Philippi A, Jury C, Pividal R, Hager J, Demenais F, Basdevant A, Guy-Grand B, Froguel P
Abstract excerpt
BACKGROUND: Morbid obesity is a multifactorial disease, with a strong but almost unknown genetic component. Familial linkage studies using the candidate gene approach have been shown to be powerful tools for identifying susceptibility genes for inherited diseases. AIM OF THE STUDY: We have investigated the role of the Glucocorticoid Receptor gene (GRL) in morbid obesity. SUBJECTS: Eighty obese families were...
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