Article
Current review of genetics of human obesity: from molecular mechanisms to an evolutionary perspective.
Molecular genetics and genomics : MGG - 1 Aug 2015
Albuquerque David, Stice Eric, Rodríguez-López Raquel, Manco Licíno, Nóbrega Clévio
Abstract excerpt
It is well-known that obesity is a complex multifactorial and heterogeneous condition with an important genetic component. Recently, major advances in obesity research emerged concerning the molecular mechanisms contributing to the obese condition. This review outlines several studies and data concerning the genetics and other important factors in the susceptibility risk to develop obesity. Based in the genetic...
Topics
- Biological Evolution
- Epigenesis, Genetic
- Gene-Environment Interaction
- Genetic Predisposition to Disease
- Genetic Variation
- Genome-Wide Association Study
- Humans
- Multifactorial Inheritance
- Obesity
- Phenotype