Article
Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle.
Diabetologia - 1 Jun 1996
Yamagata K, Takeda J, Menzel S, Chen X, Eng S, Lim L R, Concannon P, Hanis C L, Spielman R S, Cox N J, Bell G I
Abstract excerpt
The expansion of trinucleotide repeats has been associated with late-onset neurodegenerative disorders. Although the genes harbouring the triplet expansions may be widely expressed, the pathological expression of these diseases is restricted to specific tissues. Non-insulin-dependent diabetes mellitus (NIDDM) shares several features with diseases resulting from such dynamic mutations including late-onset and...
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