Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterisation of human cardiac fibroblasts from explanted adult hearts.

Cell and tissue research - 1 Oct 1996

Neuss M, Regitz-Zagrosek V, Hildebrandt A, Fleck E

Abstract excerpt

Fibrosis makes an important contribution to the pathophysiological events leading to the development of heart failure in ischemic and hypertensive heart disease. Since cardiac fibroblasts are mainly responsible for the synthesis and deposition of the extracellular matrix, we have established a method for isolating and cultivating human cardiac fibroblasts from explanted human hearts. The cell yield was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Coronary Disease
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblasts

Share to Gene Expression

Share to Ligands

Share to Myocardium

Share to Phenotype

Source

Identifiers

PMID: 8781221
DOI: 10.1007/s004410050683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterisation of human cardiac fibroblasts from explanted adult hearts.PMID 8781221Read ↗

Origins of Cardiac FibroblastsSemantic proximity Read ↗

Isolation of Adult Mouse Cardiac FibroblastsSemantic proximity Read ↗

Altered physiological functions and ion currents in atrial fibroblasts from patients with chronic atrial fibrillationSemantic proximity Read ↗

Congestive heart failure effects on atrial fibroblast phenotype: differences between freshly-isolated and cultured cells.Semantic proximity Read ↗

Human left ventricular cardiac fibroblasts undergo a dynamic shift in secretome and gene expression toward a cardiac myofibroblast phenotype during early passage in typical culture expansion conditions.Semantic proximity Read ↗

Differential Expression of Matrix Metalloproteases in Human Fibroblasts with Different OriginsSemantic proximity Read ↗

Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a β-Adrenoreceptor-Dependent Mechanism.Semantic proximity Read ↗

Cardiac fibroblasts: function, regulation of gene expression, and phenotypic modulation.Semantic proximity Read ↗

Phenotypic and functional characterization of interstitial cells from human heart valves, pericardium and skin.Semantic proximity Read ↗

Rat atrial engineered heart tissue: a new in vitro model to study atrial biology.Semantic proximity Read ↗

Evidence for differences in cultured left ventricular fibroblast populations isolated from spontaneously hypertensive and Wistar-Kyoto rats.Semantic proximity Read ↗

The human adult cardiomyocyte phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.