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Article

Production and characterization of spontaneous rat heart endothelial cell lines.

Laboratory investigation; a journal of technical methods and pathology - 1 Feb 1996

Derhaag J G, Duijvestijn A M, Emeis J J, Engels W, van Breda Vriesman P J

Abstract excerpt

Endothelial cells (EC) are important regulatory cells in physiology and pathology. in vitro studies with rat EC from heart tissue are hampered by laborious isolation and purification procedures, low yield, and limited lifespan of the cells. Therefore, it is essential to obtain long-term heart EC lines that offer a more adequate in vitro system for studying rat heart EC. An ex vivo perfusion model was used to...

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PMID: 8780162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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