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Article

Regulation of hemocytes in Drosophila requires dappled cytochrome b5.

Biochemical genetics - 1 Jun 2011

Kleinhesselink Kurt, Conway Corinna, Sholer David, Huang Irvin, Kimbrell Deborah A

Abstract excerpt

A major category of mutant hematopoietic phenotypes in Drosophila is melanotic tumors or nodules, which consist of abnormal and overproliferated blood cells, similar to granulomas. Our analyses of the melanotic mutant dappled have revealed a novel type of gene involved in blood cell regulation. The dappled gene is an essential gene that encodes cytochrome b5, a conserved hemoprotein that participates in electron...

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Identifiers

PMID: 21279680
DOI: 10.1007/s10528-010-9411-7
PMCID: PMC3092937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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