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Article

SSCP pattern indicative for p53 mutation is related to advanced stage and high-grade of tongue cancer.

European journal of cancer. Part B, Oral oncology - 1 Jul 1996

Atula S, Kurvinen K, Grénman R, Syrjänen S

Abstract excerpt

53 and bcl-2 are involved in the control of cell cycling and apoptosis. Environmental factors such as smoking and radiation can disturb p53 function and predispose a cell to malignant transformation. To investigate the role of p53 mutations, as well as p53 and bcl-2 protein expression in squamous cell carcinoma of the tongue, 39 samples were analysed. Since neck metastasis is the most important prognostic factor...

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Identifiers

PMID: 8776417
DOI: 10.1016/0964-1955(96)00022-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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