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Article

Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Mar 1996

Campochiaro P A, Chang M, Ohsato M, Vinores S A, Nie Z, Hjelmeland L, Mansukhani A, Basilico C, Zack D J

Abstract excerpt

Mutant cDNAs coding for dominant-negative forms of the fibroblast growth factor receptors 1 (FGFR-1) and 2 (FGFR-2) that lack tyrosine kinase activity were ligated to a 2.2 kb DNA fragment containing the bovine rhodopsin promoter and used to generate transgenic mice. Six independent lines were ge...

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Identifiers

PMID: 8774436
PMCID: PMC6578679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8774436-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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