Article
How partial C7 deficiency with chronic and recurrent bacterial infections can mimic total C7 deficiency: temporary restoration of host C7 levels following plasma transfusion.
Immunology - 1 Jul 1996
Würzner R, Platonov A E, Beloborodov V B, Pereverzev A I, Vershinina I V, Fernie B A, Hobart M J, Lachmann P J, Orren A
Abstract excerpt
An apparently completely complement C7-deficient patient with refractory otitis media and two episodes of meningococcal disease was given therapeutic plasma transfusions in 1992 and 1994. Following these transfusions unexpected changes were found in C7 levels. Immediately after transfusion the serum C7 levels failed to rise to the expected levels but then rose to 5-10% of the normal mean during the next 5 days...
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