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Article

Clinical manifestations in humans of combined C7 and C4 deficiency associated with low levels of C2, C8, and C9.

Complement and inflammation - 1 Jan 1991

Wuillemin W A, Späth P J, Uring-Lambert B, Straub P W

Abstract excerpt

64 members of a large kindred with inherited deficiency of the seventh component of complement, C7, were studied for plasma levels of antigenetic and functional components of complement as well as for clinical manifestations of infections and autoimmune diseases. Thirty-six individuals showed a low level of C2, C7, C8, and/or C9, including null alleles for C4A and C4B. Two subjects had a complete C7 deficiency....

Topics

Adult
Alleles
Autoimmune Diseases
Bacterial Infections
Complement System Proteins
Female
Heterozygote
Homozygote
Humans
Male
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 2055010
DOI: 10.1159/000463182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2055010-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Clinical manifestations in humans of combined C7 and C4 deficiency associated with low levels of C2, C8, and C9.PMID 2055010Read ↗

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