C7 M/N protein polymorphism typing applied to inherited deficiencies of human complement proteins C6 and C7.

doi:10.1111/j.1365-2249.1992.tb06985.x

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Article

C7 M/N protein polymorphism typing applied to inherited deficiencies of human complement proteins C6 and C7.

Clinical and experimental immunology - 1 Sept 1992

Würzner R, Rance N, Potter P C, Hendricks M L, Lachmann P J, Orren A

Abstract excerpt

C7 M/N typing, the determination of the complement component C7 M/N phenotypes, was successfully used in family studies to trace haplotypes bearing C7 deficiency genes. Furthermore, it was shown to be preferable to C7 allotyping based on isoelectric focusing (IEF) since it distinguishes two commo...

Topics

Alleles
Blood Grouping and Crossmatching
Complement C6
Complement C7
Cross Reactions
Enzyme-Linked Immunosorbent Assay
Humans
MNSs Blood-Group System
Pedigree
Phenotype
Polymorphism, Genetic

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