Article
A soluble deletion mutant of the human complement receptor type 1, which lacks the C4b binding site, is a selective inhibitor of the alternative complement pathway.
European journal of immunology - 1 Aug 1996
Scesney S M, Makrides S C, Gosselin M L, Ford P J, Andrews B M, Hayman E G, Marsh H C
Abstract excerpt
The human complement receptor type 1 (CR1, CD35), is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (SCR) followed by transmembrane and cytoplasmic domains. The SCR themselves, considered in groups of seven, form long homologous...
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