Article
Angiotensin-converting enzyme and heart chymase gene polymorphisms in hypertrophic cardiomyopathy.
The American journal of cardiology - 1 Aug 1996
Pfeufer A, Osterziel K J, Urata H, Borck G, Schuster H, Wienker T, Dietz R, Luft F C
Abstract excerpt
We examined the insertion/deletion polymorphism in the angiotensin-converting enzyme gene and identified polymorphisms in the heart chymase gene to test the hypothesis that these angiotensin II-producing enzymes are associated with a monogenic cardiac disease (50 patients and 50 control subjects) as a model of cardiac hypertrophy. We found that the angiotensin-converting enzyme DD genotype was present more often...
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