Angiotensin-converting enzyme gene polymorphism in Japanese patients with hypertrophic cardiomyopathy.

doi:10.1016/0002-8703(95)90213-9

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Article

Angiotensin-converting enzyme gene polymorphism in Japanese patients with hypertrophic cardiomyopathy.

American heart journal - 1 Nov 1995

Yoneya K, Okamoto H, Machida M, Onozuka H, Noguchi M, Mikami T, Kawaguchi H, Murakami M, Uede T, Kitabatake A

Abstract excerpt

To examine the contribution of the angiotensin-converting enzyme (ACE) gene to hypertrophic cardiomyopathy (HCM), we determined the ACE insertion/deletion (I/D) polymorphism in 80 patients with HCM and 88 of their unaffected siblings and children. Patients were divided into familial or solitary H...

Topics

Aged
Base Sequence
Cardiomyopathy, Hypertrophic
Female
Genes, ras
Genotype
Humans
Japan
Male
Middle Aged
Molecular Sequence Data
Peptidyl-Dipeptidase A
Polymorphism, Genetic

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